What you’re describing sounds more like a software/infotainment bug than a setting issue, especially since: The audio source was left ON when the vehicle was shut down. The system sometimes fails to restore the previous audio state after startup. Pressing the physical volume/power knob does nothing when the condition occurs. You occasionally have to acknowledge an audio screen message and reselect the source. Interestingly, your post is now mirrored on the Lexus Owners Club forum, and there don't appear to be any owner-provided fixes posted yet. [us.lexusow...rsclub.com] My guess is that the dealer will: Check for a Lexus Interface software update. Verify whether the multimedia control module has any stored fault codes. Compare your vehicle's behavior against any Lexus technical service bulletins (TSBs) or field reports. Since the problem is intermittent, I'd recommend documenting: How often it happens. Whether Android Auto was connected when it occurred. Whether SiriusXM, FM, Bluetooth audio, or another source was active. Whether the phone was connected wirelessly or via USB. That information can help the technician reproduce the issue. Regarding Android Auto, some Lexus voice features are normally handed off to Google's voice assistant while Android Auto is active. As a result, certain native Lexus voice commands may be unavailable or limited until Android Auto is disconnected. This behavior is common across many manufacturers because Android Auto becomes the primary interface for navigation, messaging, music selection, and similar functions. [youtube.com], [wheelsjoint.com] A quick test you might try: Turn off Android Auto on the phone or in the Lexus settings. Drive for a few days using only the native Lexus system. See whether the radio startup problem still occurs. If the issue disappears, that would strongly suggest an interaction between the Lexus Interface software and Android Auto rather than a hardware problem. Out of curiosity, when the radio fails to come back on, does the infotainment system otherwise appear fully loaded and responsive, or does the entire system seem to be still "waking up" at that point? That distinction can help narrow down whether it's an audio-state issue or a broader multimedia software issue.